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Sodium channel blockers are also used as local anesthetics and anticonvulsants. [5] Sodium channel blockers have been proposed for use in the treatment of cystic fibrosis, [6] but current evidence is mixed. [7] It has been suggested that the analgesic effects of some antidepressants may be mediated in part via sodium channel blockade. [8]
Download as PDF; Printable version; ... Calcium channel blockers (100 P) ... (1 C, 66 P) S. Sodium channel blockers (1 C, 77 P) Pages in category "Antiarrhythmic agents"
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The following are medications commonly prescribed cardiac pharmaceutical agents. The specificity of the following medications is highly variable, and often are not particularly specific to a given class. As such, they are listed as are commonly accepted.
NKTR-171 – voltage-gated sodium channel blocker [15] PF-05089771 – selective Na v 1.7 and Na v 1.8 blocker [16] Ralfinamide (NW-1029) – non-selective voltage-gated sodium channel blocker, as well as other actions [17] Tetrodotoxin (9401-TTX; Tectin, Tetrodin, Tocudin) – non-selective voltage-gated sodium channel blocker [18]
Potassium channel: see also Potassium channel blocker, Potassium channel opener; Sodium channel: see also Sodium channel blocker, Sodium channel opener; Chloride channel: see also Chloride channel blocker, Chloride channel opener; Transient receptor potential channel; Ligand gated ion channels. 5-HT3: see also 5-HT3 antagonist,
A channel blocker is the biological mechanism in which a particular molecule is used to prevent the opening of ion channels in order to produce a physiological response in a cell. Channel blocking is conducted by different types of molecules, such as cations, anions, amino acids, and other chemicals.
Procainamide (PCA) is a medication of the antiarrhythmic class used for the treatment of cardiac arrhythmias.It is a sodium channel blocker of cardiomyocytes; thus it is classified by the Vaughan Williams classification system as class Ia.