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Quinine is a medication used to treat malaria and babesiosis. [5] This includes the treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available. [5] [6] While sometimes used for nocturnal leg cramps, quinine is not recommended for this purpose due to the risk of serious side effects. [5]
Serious side effects include problems with vision, muscle damage, seizures, and low blood cell levels. [ 1 ] [ 4 ] Chloroquine is a member of the drug class 4-aminoquinoline . [ 1 ] As an antimalarial, it works against the asexual form of the malaria parasite in the stage of its life cycle within the red blood cell . [ 1 ]
Common side effects include nausea, vomiting, and stomach cramps. [2] [4] Primaquine should not be given to people with glucose-6-phosphate dehydrogenase (G6PD) deficiency due to the risk of red blood cell breakdown. [4] It is often recommended that primaquine not be used during pregnancy.
Clindamycin should be given in conjunction with quinine as a 300 mg dose (in adults) four times a day for five days. The only side effects recorded in patients taking clindamycin are nausea, vomiting and abdominal pains and cramps. However these can be alleviated by consuming large quantities of water and food when taking the drug.
Quinine sulfate 300 to 325 mg once daily: this regimen is effective but not routinely used because of the unpleasant side effects of quinine. Prophylaxis against Plasmodium vivax requires a different approach given the long liver stage of this parasite. [11] This is a highly specialist area.
Rita Wilson appeared on “CBS This Morning” to discuss what she and husband Tom Hanks, experienced after they had tested positive for COVID-19, the disease caused by the coronavirus, back in March.
One of the most serious side effects is retinopathy (generally with chronic use). [ 3 ] [ 20 ] People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to increase when a person takes the medication over five years or has a cumulative dose of more than 1000 grams.
Speaking with CBS This Morning’s Gayle King, the 63-year-old actress and singer said she’s now feeling “great” more than a month after testing positive in early March.