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Adenovirus infection is a contagious viral disease, caused by adenoviruses, commonly resulting in a respiratory tract infection. [ 1 ] [ 9 ] Typical symptoms range from those of a common cold , such as nasal congestion , rhinitis , and cough , to difficulty breathing as in pneumonia . [ 9 ]
A replication-deficient chimpanzee adenovirus vaccine vector (ChAdOx1) is used by the Oxford–AstraZeneca COVID-19 vaccine that has been approved for use. [52] [53] The Janssen COVID-19 vaccine uses modified recombinant adenovirus type-26 (Ad26). [54] Recombinant adenovirus type-5 (Ad5) are being used by Ad5-nCoV, [55] ImmunityBio and UQ-CSL V451.
The 2018 United States adenovirus outbreak was an occurrence in which an unusual number of adenovirus cases were reported at two locations, one in Maryland and one in New Jersey, from September to December 2018, resulting in deaths in both states. [1] [2] At least 35 people contracted the disease in each location of the outbreak.
In March 2023, a series of Nature papers detected high titres of adeno-associated virus 2 (AAV2), alongside adenovirus and herpesvirus, in samples from a wave of childhood hepatitis. [6] One paper suggested that AAV2 co-infection may contribute to more serious liver disease than infection with only adeno- or herpesviruses and that the causal ...
The common cold or the cold is a viral infectious disease of the upper respiratory tract that primarily affects the respiratory mucosa of the nose, throat, sinuses, and larynx.
The vector is a chimpanzee adenovirus modified to avoid its replication. [1] Adenoviruses are effective vectors for inducing and boosting cellular immunity to encoded recombinant antigens. However, the widespread seroprevalence of neutralizing antibodies to common human adenovirus serotypes limits their use. Simian adenoviruses do not suffer ...
Human adenovirus 41 (HAdV-F41), is an enteric Adenovirus, a nonenveloped virus with an icosahedral nucleocapsid containing a double-stranded DNA genome. [ 1 ] It can particularly target the gastrointestinal tract to cause gastroenteritis , with symptoms similar to rotavirus gastroenteritis and norovirus . [ 2 ]
An adenovirus vaccine is a vaccine against adenovirus infection. [3] According to American CDC, "There is currently no adenovirus vaccine available to the general public. [4] It should not be confused with the strategy of using adenovirus as a viral vector to develop vaccines for other pathogens, or as a general gene carrier. [5] [6] [7]