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  2. Diagnosis of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Diagnosis_of_multiple_sclerosis

    In some reports the MRZR showed a lower sensitivity than OCB (70% vs. 100%), but a higher specificity (69% vs. 92%) for MS. [20] free light chains (FLC), specially the kappa-FLCs (kFLCs). Several authors have reported that the nephelometric and ELISA FLCs determination is comparable with OCBs as markers of IgG synthesis, and kFLCs behave even ...

  3. Magnetic resonance imaging of the brain - Wikipedia

    en.wikipedia.org/wiki/Magnetic_resonance_imaging...

    A number of different imaging modalities or sequences can be used with imaging the nervous system: T 1-weighted (T1W) images: Cerebrospinal fluid is dark. T 1-weighted images are useful for visualizing normal anatomy. T 2-weighted (T2W) images: CSF is light, but fat (and thus white matter) is darker than with T 1.

  4. Signs and symptoms of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    At five year follow-ups the overall risk of developing MS is 30%, with or without MRI lesions. Patients with a normal MRI still develop MS (16%), but at a lower rate compared to those patients with three or more MRI lesions (51%).

  5. Magnetic resonance imaging - Wikipedia

    en.wikipedia.org/wiki/Magnetic_resonance_imaging

    Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields , magnetic field gradients, and radio waves to form images of the organs in the body.

  6. Physics of magnetic resonance imaging - Wikipedia

    en.wikipedia.org/wiki/Physics_of_magnetic...

    Modern 3 Tesla clinical MRI scanner.. Magnetic resonance imaging (MRI) is a medical imaging technique mostly used in radiology and nuclear medicine in order to investigate the anatomy and physiology of the body, and to detect pathologies including tumors, inflammation, neurological conditions such as stroke, disorders of muscles and joints, and abnormalities in the heart and blood vessels ...

  7. Radiologically isolated syndrome - Wikipedia

    en.wikipedia.org/wiki/Radiologically_isolated...

    The nerve lesions in these people show dissemination in space with an otherwise normal neurological examination and without historical accounts of typical MS symptoms. [1] MRI findings that are consistent with multiple sclerosis have been observed in healthy people who underwent MRI scanning, and 50% go on to develop symptomatic MS, sometimes ...

  8. Pathology of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Pathology_of_multiple_sclerosis

    Susceptibility weighted imaging (SWI-MRI) has shown iron (hemosiderin) deposition in lesions, and helps to detect otherwise invisible lesions. [113] Abnormalities in the gray matter (Diffusion tensor MRI alterations) of the brain parenchyma are present early in the course of multiple sclerosis [114]

  9. Fluid-attenuated inversion recovery - Wikipedia

    en.wikipedia.org/wiki/Fluid-attenuated_inversion...

    Fluid-attenuated inversion recovery (FLAIR) is a magnetic resonance imaging sequence with an inversion recovery set to null fluids. For example, it can be used in brain imaging to suppress cerebrospinal fluid (CSF) effects on the image, so as to bring out the periventricular hyperintense lesions, such as multiple sclerosis (MS) plaques. [ 1 ]