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The interleukin 4 receptor is a type I cytokine receptor.It is a heterodimer, that is, composed of two subunits. IL4R is the human gene coding for IL-4Rα, the subunit which combines with either common gamma chain (γc, forming the type I IL4 receptor) or with IL-13Rα1 (forming the type II IL4 receptor).
16191 Ensembl ENSG00000113525 ENSMUSG00000036117 UniProt P05113 P04401 RefSeq (mRNA) NM_000879 NM_010558 RefSeq (protein) NP_000870 NP_034688 Location (UCSC) Chr 5: 132.54 – 132.56 Mb Chr 11: 53.61 – 53.62 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin 5 (IL-5) is an interleukin produced by type-2 T helper cells and mast cells. Function Through binding to the ...
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (T h 0 cells) to T h 2 cells. Upon activation by IL-4, T h 2 cells subsequently produce additional IL-4 in a positive feedback loop. IL-4 is produced primarily by mast cells, T h 2 cells, eosinophils and basophils. [4]
Palantir Technologies Inc's (NYSE: PLTR) federal cloud service offering has won a DoD Impact Level 6 (IL6) PA from the Defense Information Systems Agency (DISA). With this accreditation, Palantir ...
IL5 has a similar overall fold to other cytokines (e.g., IL2, IL4 and GCSF), [18] but while these exist as monomeric structures, IL5 is a homodimer. The fold contains an anti-parallel 4-alpha-helix bundle with a left handed twist, connected by a 2-stranded anti-parallel beta-sheet.
DISA operated and defended the Global Information Grid (GIG), providing information capabilities with a reach from the White House to forces at the tactical edge. DISA supported execution of military operations while simultaneously supporting peacekeeping, humanitarian assistance, and disaster-relief missions in multiple theaters around the globe.
WASHINGTON (Reuters) -The Biden administration added more than two dozen Chinese entities to a U.S. restricted trade list on Wednesday, including Zhipu AI, a developer of large language models ...
Abbott, a health care products conglomerate based in Illinois, is misleading parents and other caregivers about the nutritional value of its sugar-laden toddler milks, according to a lawsuit filed ...