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Catharanthus roseus, commonly known as bright eyes, Cape periwinkle, graveyard plant, Madagascar periwinkle, old maid, pink periwinkle, rose periwinkle, [2] is a perennial species of flowering plant in the family Apocynaceae.
It can be found in Catharanthus roseus [1] (Madagascar periwinkle) where it is the prominent compound in petals and can also be found in callus cultures. [2] Glycosides
Catharanthine and vindoline are terpenoid indole alkaloids naturally produced within the Madagascar periwinkle plant (Catharanthus roseus) whose dimerization produces the anti-cancer drugs vinblastine and vincristine. The precursor of catharanthine and vindoline is strictosidine, the common precursor of all indole alkaloids. [1]
There are eight known species. Seven are endemic to Madagascar, [4] though one, C. roseus, is widely naturalized around the world. [2] [5] The eighth species, C. pusillus, is native to India and Sri Lanka. [6] The name Catharanthus comes from the Greek for "pure flower". [7] These are perennial herbs with oppositely or almost oppositely ...
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[111] [45] The Vinca alkaloids vincristine and vinblastine, used as anti-cancer drugs, were discovered in the 1950s from the Madagascar periwinkle, Catharanthus roseus. [ 112 ] Hundreds of compounds have been identified using ethnobotany , investigating plants used by indigenous peoples for possible medical applications. [ 113 ]
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