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Patients with severe vitamin D deficiency will require treatment with a loading dose; its magnitude can be calculated based on the actual serum 25-hydroxy-vitamin D level and body weight. [ 26 ] There are conflicting reports concerning the relative effectiveness of cholecalciferol (D 3 ) versus ergocalciferol (D 2 ), with some studies ...
o 2, o 2 both eyes "O 2" usually means oxygen or oxygen therapy: o.d. omni die: every day (once daily) (preferred to "qd" in the UK [10]) o.d. oculus dexter: right eye o can be mistaken as an a which could read "a.d.", meaning right ear, confusion with "omni die" o.m. omni mane: every morning omn. bih. omni bihora: every 2 hours omn. hor. omni ...
Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body. [1] [7] [2] One nanogram per millilitre (1 ng/mL) is equivalent to 2.5 nanomoles per litre (2.5 nmol/L). Severe deficiency: < 12 ng/mL = < 30 nmol/L [2]
Vitamin D 2 (ergocalciferol) and vitamin D 3 (cholecalciferol) share a similar but not identical mechanism of action. [3] Metabolites produced by vitamin D 2 are named with an er-or ergo-prefix to differentiate them from the D 3-based counterparts (sometimes with a chole-prefix). [12]
Calcium/cholecalciferol is a combination of a calcium salt and vitamin D 3 (cholecalciferol). It is used to prevent and treat lack of calcium and vitamin D in the elderly, as well for osteoporosis in combination with other medications. [1] [2]
Calcifediol is the precursor for calcitriol, the active form of vitamin D. [3] [4] It is synthesized in the liver, by hydroxylation of cholecalciferol (vitamin D 3) at the 25-position. [3] This enzymatic 25-hydroxylase reaction is mostly due to the actions of CYP2R1 , present in microsomes , although other enzymes such as mitochondrial CYP27A1 ...
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