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Zigler's role as Principal Investigator for the ProDisc, Synthes Spine's artificial disc replacement system, was to monitor all the clinical ProDisc cases done at the Texas Back Institute, and also to serve as a resource to Synthes on questions about cases done at all of the 19 other investigative sites.
The second disc replacement to achieve wide clinical use was the prodisc total disc replacement; it continues to have worldwide use today. Designed by French orthopedic spine surgeon Thiery Marnay, M.D., in the late 1980s, early implantations of the prodisc device began in 1990, with a 7-11 year follow-up published in 2005.
Synthes Holding AG (formerly Synthes-Stratec) is a multinational medical device manufacturer based in Solothurn, Switzerland and West Chester, Pennsylvania, United States. It is the world's largest maker of implants to mend bone fractures, [ 2 ] and also produces surgical power tools and advanced biomaterials .
Hybrid Synergy Drive (HSD), also known as Toyota Hybrid System II, is the brand name of Toyota Motor Corporation for the hybrid car drive train technology used in vehicles with the Toyota and Lexus marques.
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Prodisc; Pressing-Media www.pressing-media.com; PrimeDisc [22] Princo Corp [23] (seems to have stopped, as of 2020 they no longer appear on their home page) [24] Panasonic (Matsushita) (made DVD-RAM, stopped due to shrinking demand; made Blu-ray discs for recording until Feb 2023 [25] [26])
The two-mode hybrid drive system manufactured by Allison Transmission was first used in New Flyer transit buses which entered revenue service in 2004; [31] in testing at the National Renewable Energy Laboratory, measured fuel economy improved from 1.46–3.03 mpg ‑US (161–78 l/100 km) for conventional diesel bus to 2.56–3.98 mpg ‑US (91 ...
Two-hybrid screening (originally known as yeast two-hybrid system or Y2H) is a molecular biology technique used to discover protein–protein interactions (PPIs) [1] and protein–DNA interactions [2] [3] by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively.