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The gall bladder should respond and begin emptying into the duodenum, the amount of bile ejected can then be calculated as an ejection fraction (EF). An EF < 35% is considered to be diagnostic of biliary dyskinesia and suitable for cholecystectomy to be considered.
Biliary dyskinesia is a disease with the abnormal release of bile from the gallbladder leading to chronic biliary colic. Diagnosis is based on several studies examining the most common cause of gallstones and looking at the ejection fraction through a HIDA scan with cholecystokinin. This hormone causes bile release from the gallbladder. [19]
An ejection fraction (EF) is the volumetric fraction (or portion of the total) of fluid (usually blood) ejected from a chamber (usually the heart) with each contraction (or heartbeat). It can refer to the cardiac atrium , [ 1 ] cardiac ventricle , [ 2 ] gall bladder, [ 3 ] or leg veins, [ 4 ] although if unspecified it usually refers to the ...
The human gallbladder is a hollow grey-blue organ that sits in a shallow depression below the right lobe of the liver. [2] In adults, the gallbladder measures approximately 7 to 10 centimetres (2.8 to 3.9 inches) in length and 4 centimetres (1.6 in) in diameter when fully distended. [3]
Once tissue has died, the gallbladder is at greatly increased risk of rupture (perforation), which can cause sharp pain. Rupture can also occur in cases of chronic cholecystitis. [13] Rupture is a rare but serious complication that leads to abscess formation or peritonitis. [14] Massive rupture of the gallbladder has a mortality rate of 30%. [13]
Abnormal gallbladder function and/or blood flow; Gall stones; Sphincter of Oddi dysfunction; Hiatal hernia [14] Cardiac bridge (Coronary occluding reflexes triggered by coronary reflexes) Enteric disease; Aneructonia, the loss of the ability to belch (continuous or intermittent) [citation needed]
[5] [31] Surgical treatment in asymptomatic patients has been recommended if the ejection fraction falls to 50% or below, in the face of progressive and severe left ventricular dilatation, or with symptoms or abnormal response to exercise testing. For both groups of patients, surgery before the development of worsening ejection fraction/LV ...
Rokitansky–Aschoff sinuses are pseudodiverticula or pockets in the wall of the gallbladder.They may be microscopic or macroscopic. Histologically, they are outpouchings of gallbladder mucosa into the gallbladder muscle layer and subserosal tissue as a result of hyperplasia and herniation of epithelial cells through the fibromuscular layer of the gallbladder wall.