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Iron(II) fumarate, also known as ferrous fumarate, is the iron(II) salt of fumaric acid, occurring as a reddish-orange powder, used to supplement iron intake. It has the chemical formula C 4 H 2 Fe O 4 .
Some preparations of EE/NETA used in birth control additionally contain an iron supplement in the form of ferrous fumarate. [ 4 ] Norethindrone acetate and ethinyl estradiol have been approved in the US for the prevention of pregnancy as a swallowable tablet since 1968. [ 5 ]
Ferrous salts are available as a generic medication and over the counter. [11] Slow release formulations, while available, are not recommended. [ 12 ] In 2021, ferrous sulfate was the 105th most commonly prescribed medication in the United States, with more than 6 million prescriptions.
Examples of iron preparation include ferrous sulfate, ferrous gluconate, and ferrous fumarate. It can be administered orally, and by intravenous injection, or intramuscular injection. [1] Early Iron Supplement for Anemia. Iron preparation stimulates red blood cell production.
Ferrous salt/folic acid is a supplement used to prevent iron deficiency and folic acid deficiency during pregnancy. [1] It can also be used to treat iron deficiency anemia. [1] It is a fixed dose combination of ferrous salt and folic acid. [1] It is taken by mouth. [1] Side effects may include dark stools, constipation, and abdominal pain. [1]
Some preparations of EE/LNG additionally contain an iron supplement in the form of ferrous bisglycinate or ferrous fumarate. [4] Side effects can include nausea, headache, blood clots, breast pain, depression, and liver problems. [3]
Iron is stored in many organisms in the form of ferritin, which is a ferrous oxide encased in a solubilizing protein sheath. [10] Species of bacteria, including Shewanella oneidensis, Geobacter sulfurreducens and Geobacter metallireducens, use iron oxides as terminal electron acceptors. [11]
Fumarate hydratase deficiency [1] Fumarate is converted to malate by fumarase . Fumarase deficiency (or fumaric aciduria ) is an exceedingly rare autosomal recessive metabolic disorder in the Krebs cycle , characterized by a deficiency of the enzyme fumarate hydratase , which causes a buildup of fumaric acid in the urine and a deficiency of ...