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Coenzyme Q 10 (CoQ 10 / ˌ k oʊ k j uː ˈ t ɛ n /), also known as ubiquinone, is a naturally occurring biochemical cofactor (coenzyme) and an antioxidant produced by the human body. [ 1 ] [ 2 ] [ 3 ] It can also be obtained from dietary sources, such as meat, fish, seed oils, vegetables, and dietary supplements .
A ubiquinol is an electron-rich (reduced) form of coenzyme Q (ubiquinone). The term most often refers to ubiquinol-10 , with a 10-unit tail most commonly found in humans. The natural ubiquinol form of coenzyme Q is 2,3-dimethoxy-5-methyl-6-poly prenyl-1,4-benzoquinol, where the polyprenylated side-chain is 9-10 units long in mammals .
Cytochrome b binds a ubiquinol and a ubiquinone. The 2Fe/2S center and B L heme each pull an electron off the bound ubiquinol, releasing two protons into the intermembrane space. One electron is transferred to cytochrome c 1 from the 2Fe/2S centre, whilst another is transferred from the B L heme to the B H Heme.
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NAD + to NADH. FMN to FMNH 2. CoQ to CoQH 2.. Complex I is the first enzyme of the mitochondrial electron transport chain.There are three energy-transducing enzymes in the electron transport chain - NADH:ubiquinone oxidoreductase (complex I), Coenzyme Q – cytochrome c reductase (complex III), and cytochrome c oxidase (complex IV). [1]
Abbreviation Meaning q: each, every (from Latin quaque) : q15: every 15 minutes q6h q6° once every 6 hours q2wk: once every 2 weeks qAc Before every meal (from Latin quaque ante cibum)
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