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In modern typical usage, the solution is applied to the wound once daily for lightly to moderately exudative wounds, and twice daily for heavily exudative wounds or highly contaminated wounds. [ 3 ] The healthy skin surrounding the wound should preferably be protected with a moisture barrier ointment (e.g., petroleum jelly ) or skin sealant as ...
During the 1960s, both were available over the counter in the US. After the ban, pHisoDerm was reformulated without hexachlorophene, and continued to be sold over-the-counter, while pHisoHex , (which contained 3% hexachlorophene - 3 times the legal limit imposed in 1972), [ 7 ] became available as a prescription body wash.
An over-the-counter drug, its advertising was carried out by Warren Muller Dulubowsky. [3] By April 1989, Sterling Drug was owned by Eastman Kodak. Three Sterling brands, Haley's M-O, Philips' Milk of Magnesia, and Phisoderm, were being advertised by N.W. Ayer. [4] In 1991, the Phisoderm account was picked up by Ammirati & Puris of New York ...
Chlorhexidine came into medical use in the 1950s [15] and is available over the counter in the United States. [9] It is on the World Health Organization's List of Essential Medicines. [16] In 2022, it was the 230th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [17] [18]
Merbromin's best-known use is as a topical antiseptic to treat minor wounds, burns, and scratches. [3] It is also used in the antisepsis of the umbilical cord, [4] and the antisepsis of wounds with inhibited scar formation, such as neuropathic ulcers and diabetic foot sores. [5]
For these purposes PVP-I has been formulated at concentrations of 7.5–10.0% in solution, spray, surgical scrub, ointment, and swab dosage forms; however, use of 10% povidone-iodine though recommended, is infrequently used, as it is poorly accepted by health care workers and is excessively slow to dry. [11] [12]