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A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response.TNF is involved in autoimmune and immune-mediated disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma, so TNF inhibitors may be used in their ...
The precise mechanism by which altretamine exerts its anti-cancer effect is unknown but it is classified by MeSH as an alkylating antineoplastic agent. [5] This unique structure is believed to damage tumor cells through the production of the weakly alkylating species formaldehyde, a product of CYP450-mediated N-demethylation. Administered ...
Mast cell stabilizers are given as prophylactic treatment to prevent exacerbation of asthmatic symptoms. [22] For asthma maintenance therapy, mast cell stabilizers are taken by inhalation. [2] Common adverse effects of Mast cell stabilizers include mouth dryness, cough, throat irritation, nasal congestion and bronchospasm. [23]
Formaldehyde inhaled at this concentration may cause headaches, a burning sensation in the throat, and difficulty breathing, and can trigger or aggravate asthma symptoms. [70] [71] The CDC considers formaldehyde as a systemic poison. Formaldehyde poisoning can cause permanent changes in the nervous system's functions. [72]
A wide range of studies have linked formaldehyde to certain cancers, including uterine cancer and blood cancer. Some companies have responded by developing formaldehyde-free formulas or by clearly ...
The Environmental Protection Agency (EPA) has determined that breathing in formaldehyde, a chemical that’s used in building materials and hair straighteners, can cause cancer. In a toxicological ...
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