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Ziconotide. Ziconotide, sold under the brand name Prialt, also called intrathecal ziconotide (ITZ) because of its administration route, is an atypical analgesic agent for the amelioration of severe and chronic pain. Derived from Conus magus, a cone snail, it is the synthetic form of an ω- conotoxin peptide. [2]
A conotoxin is one of a group of neurotoxic peptides isolated from the venom of the marine cone snail, genus Conus. Conotoxins, which are peptides consisting of 10 to 30 amino acid residues, typically have one or more disulfide bonds. Conotoxins have a variety of mechanisms of actions, most of which have not been determined.
This is an accepted version of this page This is the latest accepted revision, reviewed on 11 September 2024. Film series This article is about the film series. For the franchise as a whole, see Pirates of the Caribbean. Pirates of the Caribbean Directed by Gore Verbinski (1–3) Rob Marshall (4) Joachim Rønning (5) Espen Sandberg (5) Screenplay by Ted Elliott (1–4) Terry Rossio (1–4 ...
Jazz Pharmaceuticals plc (a merger of Jazz Pharmaceuticals, Inc. and Azur Pharma plc) is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States. [2] One of the company's considerable products is the United States Food and Drug Administration (FDA) approved drug Xyrem ...
Conus magus. Conus magus, common name the magical cone, is a species of sea snail, a marine gastropod mollusk in the family Conidae, the cone snails and their allies. [2] Like all species within the genus Conus, these snails are predatory and venomous. Their venom contains conotoxins which have powerful neurotoxic effects.
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Cone snail. Cone snails, or cones, are highly venomous sea snails of the family Conidae. [1] Fossils of cone snails have been found from the Eocene to the Holocene epochs. [2] Cone snail species have shells that are roughly conical in shape. Many species have colorful patterning on the shell surface. [3] Cone snails are almost exclusively ...
Conidae. Conidae, with the current common name of "cone snails", is a taxonomic family (previously subfamily) of predatory sea snails, marine gastropod molluscs in the superfamily Conoidea. The 2014 classification of the superfamily Conoidea groups only cone snails in the family Conidae. Some previous classifications grouped the cone snails in ...