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The Naja Kaouthia venom is a member of the snake three-finger toxin family in the subfamily type II alpha-neurotoxin. The lethal dose (LD50) of α-cobratoxin is 0,1 mg/kg by intravenous injection into mice15. The toxin occurs as a monomer but can form a homodimer or heterodimers with cytotoxins 1,2, and 3 through disulfide linkage.
When distressed the rinkhals will spread its hood, showing its distinctive striped neck. As a defense mechanism, the rinkhals will spit venom. [8] They will normally spit from a reared position, lunging and hissing while doing so. The rinkhals has ample control over its venom glands, and can accurately spit venom at ranges up to three meters [8].
It uses its venom primarily as a means of defense. The spitting cobra has the ability to direct venom up to three metres away from its location. [1] The trajectory of the venom that the cobra sprays is not at random. The spitting cobra has evolved to aim the venom that it spits into or as close as possible to the antagonist’s face and eyes. [1]
The most important factors in the difference of mortality rates among victims envenomated by cobras is the severity of the bite and which cobra species caused the envenomation. The Caspian cobra (N. oxiana) and the Philippine cobra (N. philippinensis) are the two cobra species with the most toxic venom based on LD 50 studies on mice.
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The king cobra (Ophiophagus hannah) is a species complex of snakes endemic to Asia.With an average of 3.18 to 4 m (10.4 to 13.1 ft) and a record length of 5.85 m (19.2 ft), [2] it is the world's longest venomous snake and among the heaviest.
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Ophanin is a toxin found in the venom of the King Cobra (Ophiophagus hannah), which lives throughout South East Asia. This toxin belongs to the cysteine-rich secretory protein (CRISP) family. Ophanin weakly blocks the contraction of smooth muscles elicited by high potassium-induced depolarization , [ 1 ] suggesting that it inhibits voltage ...