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While some studies suggest that there are minimal differences in side effects between asthma patients and non-asthma patients, beta 1 blockers are generally avoided in patients with asthma or chronic obstructive pulmonary disease due to their potential to block beta 2 receptors, particularly at high doses.
Due to its vasodilation properties, the common side effects of salmeterol are dizziness, sinus infection, and; migraine headaches. Other side effects muscle tremors, hypokalemia due to direct effect on beta-2 receptors on skeletal muscle. In most cases, salmeterol side effects are minor and either do not require treatment or can easily be treated.
The common side effects of Tedral include gastrointestinal disturbances, dizziness, headache and lightheadedness. [ 3 ] [ 4 ] [ 5 ] However, at high dose, it may lead to cardiac arrhythmias , hypertension , seizures or other serious cardiovascular and/or central nervous system adverse effects.
This product was approved by the FDA in May 2013 as once-daily inhaled therapy for the treatment of chronic obstructive pulmonary disease (COPD) with umeclidinium bromide: Anoro Ellipta. Umeclidinium bromide is a long-acting muscarinic antagonist. [14]
Beta-blockers with intrinsic sympathomimetic activity: acebutolol, pindolol; Some common side effects include increased airway resistance for non-selective beta-blockers, exacerbation of peripheral vascular diseases, and hypotension [15] Beta-blockers are contraindicated in patients with second- or third-degree atrioventricular block.
Like other non-selective beta blockers, levobunolol is contraindicated in patients with airway diseases such as asthma and severe chronic obstructive pulmonary disease (COPD), as well as heart problems such as sinus bradycardia, second- or third-degree atrioventricular block, sick sinus syndrome, and cardiogenic shock.
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