Search results
Results From The WOW.Com Content Network
As Pol II reaches the end of a gene, two protein complexes carried by the CTD, CPSF (cleavage and polyadenylation specificity factor) and CSTF (cleavage stimulation factor), recognize the poly-A signal in the transcribed RNA. [35] Poly-A-bound CPSF and CSTF recruit other proteins to carry out RNA cleavage and then polyadenylation.
Transcription is the process of copying a segment of DNA into RNA for the purpose of gene expression.Some segments of DNA are transcribed into RNA molecules that can encode proteins, called messenger RNA (mRNA).
Sequencing RNA in its native form preserves modifications like methylation, allowing them to be investigated directly and simultaneously. [21] Another benefit of single-molecule RNA-Seq is that transcripts can be covered in full length, allowing for higher confidence isoform detection and quantification compared to short-read sequencing.
RNA is transcribed in the nucleus; after processing, it is transported to the cytoplasm and translated by the ribosome. Finally, the mRNA is degraded. Finally, the mRNA is degraded. In molecular biology , messenger ribonucleic acid ( mRNA ) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene , and is read by ...
Telomeric repeat–containing RNA (TERRA) is a long non-coding RNA transcribed from telomeres - repetitive nucleotide regions found on the ends of chromosomes that function to protect DNA from deterioration or fusion with neighboring chromosomes. TERRA has been shown to be ubiquitously expressed in almost all cell types containing linear ...
Based on the needs of a given cell, certain DNA sequences are transcribed to produce a variety of RNA products to be translated into functional proteins for cellular use. To initiate the transcription process in a cell's nucleus, DNA double helices are unwound and hydrogen bonds connecting compatible nucleic acids of DNA are broken to produce ...
Protein synthesis can be divided broadly into two phases: transcription and translation. During transcription, a section of DNA encoding a protein, known as a gene, is converted into a molecule called messenger RNA (mRNA). This conversion is carried out by enzymes, known as RNA polymerases, in the nucleus of the cell. [2]
In fact, many prokaryotic genes occur in operons, which are a series of genes that work together to code for the same protein or gene product and are controlled by a single promoter. [2] Bacterial RNA polymerase is made up of four subunits and when a fifth subunit attaches, called the sigma factor (σ-factor), the polymerase can recognize ...