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Amiodarone inhibits peripheral conversion of thyroxine to triiodothyronine; also interferes with thyroid hormone action. [citation needed] Lithium inhibits thyroid hormone release. [citation needed] Phenobarbitone, phenytoin, carbamazepine, rifampin induce metabolic degradation of triiodothyronine (T 3) and thyroxine (T 4). [citation needed]
The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans, it is a butterfly-shaped gland located in the neck below the Adam's apple. It consists of two connected lobes. The lower two thirds of the lobes are connected by a thin band of tissue called the isthmus (pl.: isthmi).
DIT is a modulator of the enzyme thyroid peroxidase (which is involved in the production of thyroid hormones). [1] Triiodothyronine is formed, when diiodotyrosine is combined with monoiodotyrosine (in the colloid of the thyroid follicle). Two molecules of DIT combine to make the thyroid hormone thyroxine ('T4' and 'T3').
Thyroid is a medical journal in the field of endocrinology, covering research on diseases of the thyroid. It is the official journal of the American Thyroid Association and published by Mary Ann Liebert, Inc.
Jostel's TSH index (TSHI or JTI), also referred to as Jostel's thyrotropin index or Thyroid Function index (TFI), is a method for estimating the thyrotropic (i.e. thyroid stimulating) function of the anterior pituitary lobe in a quantitative way. [1] [2] The equation has been derived from the logarithmic standard model of thyroid homeostasis.
Barry John Durrant-Peatfield (November 1936 – 27 August 2023) was a British medical practitioner specialising in metabolic disorders namely, hypothyroidism.. Durrant-Peatfield submitted to voluntary erasure from the medical register as an alternative to having his license suspended for the use of unapproved diagnostic tests and treatments such as whole thyroid extracts (NDT).
Broda Otto Barnes (14 April 1906 – 1 November 1988) was an American physician and professor of medicine who studied endocrine dysfunction, particularly hypothyroidism. [4] [5] In the 1970s, Barnes published several books arguing that hypothyroidism was underdiagnosed in the U.S. and was responsible for a wide range of health problems.
TSH (with a half-life of about an hour) stimulates the thyroid gland to secrete the hormone thyroxine (T 4), which has only a slight effect on metabolism. T 4 is converted to triiodothyronine (T 3), which is the active hormone that stimulates metabolism. About 80% of this conversion is in the liver and other organs, and 20% in the thyroid ...