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Ataxia–telangiectasia (AT or A–T), also referred to as ataxia–telangiectasia syndrome or Louis–Bar syndrome, [1] is a rare, neurodegenerative disease causing severe disability. Ataxia refers to poor coordination and telangiectasia to small dilated blood vessels, both of which are hallmarks of the disease. [ 2 ]
She had complaints of dysarthria, dysphagia, dizziness, nausea, vomiting, and weakness of left arm and leg. After looking into her medical records there was only a sudden development of these symptoms one hour before being admitted to the hospital and additional symptoms of dysphagia, dysarthria, and weakness of left arm and leg. [ 10 ]
Ataxia (from Greek α- [a negative prefix] + -τάξις [order] = "lack of order") is a neurological sign consisting of lack of voluntary coordination of muscle movements that can include gait abnormality, speech changes, and abnormalities in eye movements, that indicates dysfunction of parts of the nervous system that coordinate movement, such as the cerebellum.
Certain signs and symptoms of MSA also occur with other disorders, such as Parkinson's disease, making the diagnosis more difficult. [ 40 ] [ 41 ] [ 42 ] Features characteristic of OPCA include progressive cerebellar ataxia , leading to clumsiness in body movements, veering from midline when walking, wide-based stance, and falls without signs ...
The symptoms of vestibulocerebellar syndrome vary among patients but are typically a unique combination of ocular abnormalities including nystagmus, poor or absent smooth pursuit (ability of the eyes to follow a moving object), strabismus (misalignment of the eyes), diplopia (double vision), oscillopsia (the sensation that stationary objects in the visual field are oscillating) and abnormal ...
Vertebrobasilar insufficiency (VBI) describes a temporary set of symptoms due to decreased blood flow in the posterior circulation of the brain.The posterior circulation supplies the medulla, pons, midbrain, cerebellum and (in 70-80% of people) supplies the posterior cerebellar artery to the thalamus and occipital cortex. [1]
The usual symptoms are tinnitus, ataxia, difficulty with coordination, vertigo, nausea, vomiting, and hearing loss. [10] [11] It is not unusual for other symptoms of decompression sickness to be present simultaneously, which can make diagnosis easier, but sometimes only vestibular symptoms manifest.
Susac's syndrome; Other names: Retinopathy-encephalopathy-deafness associated with microangiopathy: Sagittal T1 image in a 19-year-old woman with Susac's syndrome showing the pathognomonic central callosal "holes" (microinfarcts) of SS.