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In addition, the FDA has reported on life-threatening drug interactions that may be possible when co-administered with triptans and other drugs acting on serotonin pathways leading to increased risk for serotonin syndrome. [56] Duloxetine should also be avoided in hepatic impairment such as cirrhosis. [57]
Bisacodyl is an organic compound that is used as a stimulant laxative drug. It works directly on the colon to produce a bowel movement. It is typically prescribed for relief of episodic and chronic constipation and for the management of neurogenic bowel dysfunction, as well as part of bowel preparation before medical examinations, such as for a colonoscopy.
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds ...
However, there may be some short-term side effects, such as diarrhea, nausea, bloating, vomiting, or stomach pain. Normally, these are manageable, but if used for weight loss, the side effects of ...
Examples: senna, bisacodyl [3] Prolonged use of stimulant laxatives can create drug dependence by damaging the colon's haustral folds, making users less able to move feces through their colon on their own. A study of patients with chronic constipation found that 28% of chronic stimulant laxative users lost haustral folds over the course of one ...
Dulcolax may refer to: Dulcolax, a trade name of bisacodyl, a stimulant laxative drug that increases bowel movement; Dulcolax Balance, a trade name of macrogol, an osmotic laxative; Dulcolax Stool Softener, a trade name of dioctyl sodium sulfosuccinate, a common ingredient in products such as laxatives
Any antiretroviral drug: Black tar heroin: Whoonga, Nyaope [8] Widespread use in South Africa. Whoonga is classically reputed to be a combination of heroin with antiretroviral drugs such as ritonavir and/or efavirenz, often combined with additional drugs such as cannabis or hashish, methamphetamine and/or methaqualone: Any deliriant or diphen ...
Drug interactions, prolonged QT. [14] Drotrecogin alfa (Xigris) 2011 Worldwide Lack of efficacy as shown by PROWESS-SHOCK study [19] [20] [21] Ebrotidine: 1998 Spain Hepatotoxicity. [3] Efalizumab (Raptiva) 2009 Germany Withdrawn because of increased risk of progressive multifocal leukoencephalopathy [14] Encainide: 1991 UK, US Ventricular ...