Ads
related to: diuretic drugs medication
Search results
Results From The WOW.Com Content Network
There are several categories of diuretics. All diuretics increase the excretion of water from the body, through the kidneys. There exist several classes of diuretic, and each works in a distinct way. Alternatively, an antidiuretic, such as vasopressin (antidiuretic hormone), is an agent or drug which reduces the excretion of water in urine.
Loop diuretics usually have a ceiling effect whereby doses greater than a certain maximum amount will not increase the clinical effect of the drug. Also, there is a threshold minimum concentration of loop diuretics that needs to be achieved at the thick ascending limb to enable the onset of abrupt diuresis. [10]
Its effects are opposite that of a diuretic. The major endogenous antidiuretics are antidiuretic hormone (ADH; also called vasopressin) and oxytocin . Both of those are also used exogenously as medications in people whose bodies need extra help with fluid balance via suppression of diuresis.
Thiazide (/ ˈ θ aɪ ə z aɪ d /) refers to both a class of sulfur-containing organic molecules [1] and a class of diuretics based on the chemical structure of benzothiadiazine. [2] The thiazide drug class was discovered and developed at Merck and Co. in the 1950s. [3]
Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]
In 2022, it was the 24th most commonly prescribed medication in the United States, with more than 23 million prescriptions. [8] [9] In 2020/21 it was the twentieth most prescribed medication in England. [10] It is on the World Anti-Doping Agency's banned drug list due to concerns that it may mask other drugs. [11]