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Pterostilbene is considered to be a corrosive substance, is dangerous upon exposure to the eyes, and is an environmental toxin, especially to aquatic life. [1] A preliminary study of healthy human subjects given pterostilbene for 6–8 weeks, showed pterostilbene to be safe for human use at dosages up to 250 mg per day, although this study did not assess metabolic effects on the lipid profile.
Elysium Health was founded in 2014 by Leonard Guarente, Dan Alminana, and Eric Marcotulli. [1] In 2015, Elysium introduced its first product, Basis, which contains nicotinamide riboside and pterostilbene. [2] [3] In December 2016, Elysium received an investment of $20 million in Series B funding.
Many syntheses have been developed. One popular route entails reduction of benzoin using zinc amalgam. [6]C 6 H 5 –CH(OH)–C(=O)–C 6 H 5, trans-C 6 H 5 –CH=CH–C 6 H 5. Both isomers of stilbene can be produced by decarboxylation of α-phenylcinnamic acid, trans-stilbene being produced from the (Z)-isomer of the acid.
A review of 136 patients in seven studies who were given more than 500 mg for a month showed 25 cases of diarrhea, 8 cases of abdominal pain, 7 cases of nausea, and 5 cases of flatulence. [52] A 2018 review of resveratrol effects on blood pressure found that some people had increased frequency of bowel movements and loose stools .
Human Longevity, Inc. is a San Diego–based venture launched by Craig Venter, Robert Hariri and Peter Diamandis in 2013. Its goal is to build the world's most comprehensive database on human genotypes and phenotypes, and then subject it to machine learning so that it can help develop new ways to fight diseases associated with aging . [ 1 ]
Stilbestrol, or stilboestrol, also known as 4,4'-dihydroxystilbene or 4,4'-stilbenediol, is a stilbenoid nonsteroidal estrogen [1] and the parent compound of a group of more potent nonsteroidal estrogen derivatives that includes, most notably, diethylstilbestrol (DES).
Nathan Pritikin (August 29, 1915 – February 21, 1985) was an American inventor, engineer, nutritionist and longevity researcher. [1] [2] He promoted the Pritikin diet, a high-carbohydrate low-fat plant-based diet combined with regular aerobic exercise to prevent cardiovascular disease. [3]
Ingredient lists were also present in the product information sections for the powdered and capsule forms of the drug on Amazon.com. [14] The corporation denies that the list is the secret formula. [ 15 ]
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