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The permutation by duplication mechanism for producing a circular permutation. First, a gene 1-2-3 is duplicated to form 1-2-3-1-2-3. Next, a start codon is introduced before the first domain 2 and a stop codon after the second domain 1, removing redundant sections and resulting in a circularly permuted gene 2-3-1.
Print/export Download as PDF; Printable version; ... Circular permutation in proteins; Claw-free permutation; Computing the permanent; Costas array;
A cyclic permutation consisting of a single 8-cycle. There is not widespread consensus about the precise definition of a cyclic permutation. Some authors define a permutation σ of a set X to be cyclic if "successive application would take each object of the permuted set successively through the positions of all the other objects", [1] or, equivalently, if its representation in cycle notation ...
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After the permutation the second protein (inner circle) has the sequence c-a-b. The letters N and C indicate the location of the amino- and carboxy-termini of the protein sequences and how their positions change relative to each other.