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Note that the dimensionless stress concentration factor is a function of the geometry shape and independent of its size. [4] These factors can be found in typical engineering reference materials. Stress concentration around an elliptical hole in a plate in tension. E. Kirsch derived the equations for the elastic stress distribution around a hole.
Stress is a measure of the average amount of force exerted per unit area. The stress distribution can be obtained from known theoretical [ 1 ] or numerical ( Finite element method ) analysis. The researcher who builds up the force lines can choose a magnitude of the internal force and the initial border where the drawing procedure starts.
Frank–Starling curve. “The heart will pump what it receives”- Starling’s law of the heart. The Frank–Starling mechanism describes the ability of the heart to change its force of contraction (and, hence, stroke volume) in response to changes in venous return. In other words, if the end-diastolic volume increases, there is a ...
Major factors influencing cardiac output – heart rate and stroke volume, both of which are variable. [1]In cardiac physiology, cardiac output (CO), also known as heart output and often denoted by the symbols , ˙, or ˙, [2] is the volumetric flow rate of the heart's pumping output: that is, the volume of blood being pumped by a single ventricle of the heart, per unit time (usually measured ...
The underlying cause of the Bowditch effect is an increase in the calcium concentration in the sarcoplasmic reticulum of cardiac muscle cells, and its increased release into sarcoplasm. [ 3 ] One of the explanations for an increase in the intracellular calcium concentration is the inability of the Na + /K + -ATPase to keep up with influx of ...
The general trend given by the Goodman relation is one of decreasing fatigue life with increasing mean stress for a given level of alternating stress. The relation can be plotted to determine the safe cyclic loading of a part; if the coordinate given by the mean stress and the alternating stress lies under the curve given by the relation, then ...
Impedance cardiography (ICG) is a non-invasive technology measuring total electrical conductivity of the thorax and its changes in time to process continuously a number of cardiodynamic parameters, such as stroke volume (SV), heart rate (HR), cardiac output (CO), ventricular ejection time (VET), pre-ejection period and used to detect the impedance changes caused by a high-frequency, low ...
The degree of binding depends upon the concentration of calcium ions in the cell. Within an in vivo intact heart, the action/response of the sympathetic nervous system is driven by precisely timed releases of a catecholamine , which is a process that determines the concentration of calcium ions in the cytosol of cardiac muscle cells.