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Virtually all cervical cancer cases (99%) are linked to genital human papillomavirus infection (HPV); [14] [5] [6] most who have had HPV infections, however, do not develop cervical cancer. [3] [15] HPV 16 and 18 strains are responsible for approximately 70% of cervical cancer cases globally and nearly 50% of high grade cervical pre-cancers.
Because of the link between HPV and cervical cancer, the ACS currently recommends early detection of cervical cancer in average-risk asymptomatic adults primarily with cervical cytology by Pap smear, regardless of HPV vaccination status. Women aged 30–65 should preferably be tested every 5 years with both the HPV test and the Pap test.
Between 2012 and 2019, cervical cancer incidence among women ages 20 to 24 dropped by 65%, an American Cancer Society report found. In addition, fewer teens and young adults get genital warts as a ...
By contrast, HPV types 6 and 11 are considered low risk because they’re not associated with cancer, but they can cause genital warts. HPV spreads through sexual contact, including direct genital ...
“We are highlighting that HPV screening, as the primary screening for women ages 30 to 65, is the best balance between the benefits and the harms in finding cervical cancer, and that should be ...
The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is thought that the high-risk HPV infections have the ability to inactivate tumor suppressor genes such as the p53 gene and the RB gene, thus allowing the infected cells to grow unchecked and accumulate successive mutations, eventually leading to cancer.
HPV, the human papillomavirus, causes six types of cancer, including cervical cancer. Among women aged 20 to 24, cervical cancer incidence dropped by 65% from 2012 to 2019, according to a report ...
Frazer and Jian Zhou developed and patented the basic technology behind the HPV vaccine against cervical cancer at the University of Queensland. Researchers at the National Cancer Institute, Georgetown University, and University of Rochester also contributed to the further development of the cervical cancer vaccine in parallel. [2] [3]
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