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Animal trypanosomiasis, also known as nagana and nagana pest, or sleeping sickness, is a disease of vertebrates. The disease is caused by trypanosomes of several species in the genus Trypanosoma such as T. brucei. T. vivax causes nagana mainly in West Africa, although it has spread to South America. [1]
The two Trypanosoma brucei subspecies that cause human trypanosomiasis, T. b. gambiense and T. b. rhodesiense, are indistinguishable morphologically. The trypanosomes' length range is 14 to 33 μm; source: CDC. The gold standard for diagnosis is the identification of trypanosomes in a sample by microscopic examination.
Trypanosomiasis or trypanosomosis is the name of several diseases in vertebrates caused by parasitic protozoan trypanosomes of the genus Trypanosoma. In humans this includes African trypanosomiasis and Chagas disease .
T. equiperdum, which causes dourine or covering sickness in horses and other Equidae, it can be spread through coitus. T. evansi, which causes one form of the disease surra in certain animals including camels [20] (a single case report of human infection in 2005 in India [21] was successfully treated with suramin [22]) T. everetti, in birds
T. brucei rhodesiense which causes fast onset acute trypanosomiasis in humans. A highly zoonotic parasite, it is prevalent in southern and eastern Africa, where game animals and livestock are thought to be the primary reservoir. [45] [48] T. brucei brucei which causes animal trypanosomiasis, along with several other species of Trypanosoma. T. b.
Benznidazole and nifurtimox often cause side effects, including skin disorders, digestive system irritation, and neurological symptoms, which can result in treatment being discontinued. [ 2 ] [ 8 ] New drugs for Chagas disease are under development, [ 9 ] and while experimental vaccines have been studied in animal models, [ 10 ] [ 11 ] a human ...
Trypanosoma congolense is a species of trypanosomes and is the major pathogen responsible for the disease nagana in cattle and other animals including sheep, pigs, goats, horses and camels, dogs, [2] as well as laboratory mice. It is the most common cause of nagana in east Africa, but is also a major cause of nagana in west Africa.
This behaviour causes disease or the likelihood of disease that varies with the organism: Chagas disease in humans, dourine and surra in horses, and a brucellosis-like disease in cattle. Parasites need a host body and the haematophagous insect triatomine (descriptions "assassin bug", "cone-nose bug", and "kissing bug") is the major vector in ...