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[medical citation needed] In cases of subacute bacterial endocarditis, the causative organism (streptococcus viridans) needs previous heart valve disease to colonize. [9] On the other hand, in cases of acute bacterial endocarditis the organism can colonize on the healthy heart valve, causing the disease. [10]
Infective endocarditis is divided into the three categories of acute, subacute, and chronic based on the duration of symptoms. [11] Acute infective endocarditis refers to the presence of signs and symptoms of infective endocarditis that are present for days up to six weeks. [11]
The nodes are commonly indicative of subacute bacterial endocarditis. [4] 10–25% of endocarditis patients will have Osler's nodes. [5] Other signs of endocarditis include Roth's spots and Janeway lesions. The latter, which also occur on the palms and soles, can be differentiated from Osler's nodes because they are non-tender. [3]
Endocarditis is characterized by lesions, known as vegetations, which are masses of platelets, fibrin, microcolonies of microorganisms, and scant inflammatory cells. [1] In the subacute form of infective endocarditis, a vegetation may also include a center of granulomatous tissue, which may fibrose or calcify. [2]
Libman–Sacks endocarditis is a form of non-bacterial endocarditis that is seen in association with systemic lupus erythematosus, antiphospholipid syndrome, and malignancies. It is one of the most common cardiac manifestations of lupus (the most common being pericarditis ).
S. sanguinis may gain entrance to the bloodstream when opportunity presents (dental cleanings and surgeries) and colonize the heart valves, particularly the mitral and aortic valves, where it is the most common cause of subacute bacterial endocarditis. For this reason, oral surgeons often prescribe a short course of antibiotics to be taken a ...
While myocarditis has many etiologies and a variable constellation of signs and symptoms, many causes do not have a specific treatment thus the primary focus is on supportive care and symptom management. [17] In some cases of biopsy-proven myocarditis, the causative cell type may indicate condition specific treatments that are beneficial.
Symptoms typically include sudden onset of sharp chest pain, which may also be felt in the shoulders, neck, or back. [1] The pain is typically less severe when sitting up and more severe when lying down or breathing deeply. [1] Other symptoms of pericarditis can include fever, weakness, palpitations, and shortness of breath. [1]