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The term genome was created in 1920 by Hans Winkler, [8] professor of botany at the University of Hamburg, Germany.The website Oxford Dictionaries and the Online Etymology Dictionary suggest the name is a blend of the words gene and chromosome.
The DNA sequence assembly alone is of little value without additional analysis. [9] Genome annotation is the process of attaching biological information to sequences, and consists of three main steps: [68] identifying portions of the genome that do not code for proteins; identifying elements on the genome, a process called gene prediction, and
The most commonly used approach to genome-investigation is evolutionary genomics biology, or evo-geno, in which the genomes of two species which share a common ancestor are compared. [4] A common example of evo-geno is comparative cognitive genomics testing between humans and chimpanzees which shared an ancestor 6-7 million years ago. [5]
The term was first used by Davis in 1949, "We here propose the name phenome for the sum total of extragenic, non-autoreproductive portions of the cell, whether cytoplasmic or nuclear. The phenome would be the material basis of the phenotype, just as the genome is the material basis of the genotype." [10]
Genome-wide association studies In genome-wide association studies, researchers test the relationship of millions of genetic polymorphisms with behavioural phenotypes across the genome. [33] This approach to genetic association studies is largely atheoretical , and typically not guided by a particular biological hypothesis regarding the ...
De novo gene birth can give rise to protein-coding genes and non-coding genes from previously non-functional DNA. [33] For instance, Levine and colleagues reported the origin of five new genes in the D. melanogaster genome. [34] [35] Similar de novo origin of genes has been also shown in other organisms such as yeast, [36] rice [37] and humans ...
Human evolutionary genetics studies how one human genome differs from another human genome, the evolutionary past that gave rise to the human genome, and its current effects. Differences between genomes have anthropological , medical , historical and forensic implications and applications.
Much of the terminology of genetics and biology is unique in its pronunciation. Below each term name is a “Pronunciation” button. Click the button to hear the term spoken. Each term, regardless of its name, is pronounced. Information On Each Speaker: A brief biography and photograph of each speaker accompanies terms listed in the glossary.