Search results
Results From The WOW.Com Content Network
Some, but not all, carboxypeptidases are initially produced in an inactive form; this precursor form is referred to as a procarboxypeptidase. In the case of pancreatic carboxypeptidase A, the inactive zymogen form - pro-carboxypeptidase A - is converted to its active form - carboxypeptidase A - by the enzyme trypsin. This mechanism ensures that ...
In the duodenum, the pancreatic zymogens, trypsinogen, chymotrypsinogen, proelastase and procarboxypeptidase, are converted into active enzymes by enteropeptidase and trypsin. Chymotrypsinogen, a single polypeptide chain of 245 amino acids residues, is converted to alpha-chymotrypsin, which has three polypeptide chains linked by two of the five ...
Carboxypeptidase A2 is an enzyme that in humans is encoded by the CPA2 gene. [5] [6] [7]Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A1 and A2 forms are monomeric proteins with different biochemical properties.
This vast scope of functionality for a single protein makes it the ideal model for research regarding other zinc proteases of unknown structure.
Chymotrypsinogen. Chymotrypsinogen is an inactive precursor of chymotrypsin, a digestive enzyme which breaks proteins down into smaller peptides. Chymotrypsinogen is a single polypeptide chain consisting of 245 amino acid residues. [1]
Trypsinogen (/ ˌ t r ɪ p ˈ s ɪ n ə dʒ ə n,-ˌ dʒ ɛ n / [1] [2]) is the precursor form (or zymogen) of trypsin, a digestive enzyme.It is produced by the pancreas and found in pancreatic juice, along with amylase, lipase, and chymotrypsinogen.
12876 Ensembl ENSG00000109472 ENSMUSG00000037852 UniProt P16870 Q00493 RefSeq (mRNA) NM_001873 NM_013494 RefSeq (protein) NP_001864 NP_038522 Location (UCSC) Chr 4: 165.36 – 165.5 Mb Chr 8: 65.05 – 65.15 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Carboxypeptidase E (CPE), also known as carboxypeptidase H (CPH) and enkephalin convertase, is an enzyme that in humans is encoded ...
Enteropeptidase (also called enterokinase) is an enzyme produced by cells of the duodenum and is involved in digestion in humans and other animals. Enteropeptidase converts trypsinogen (a zymogen) into its active form trypsin, resulting in the subsequent activation of pancreatic digestive enzymes.