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Sensory side effects include paresthesias, dysesthesias, numbness, altered proprioception, and loss of dexterity in fingers and toes. Motor and autonomic symptoms are less frequent but possible. Symptoms may start days after the patient receives their first dose of chemotherapy, are dose dependent, and tend to improve after completion of treatment.
Patients with hepatocellular dysfunction may develop hair-thinning or hair loss and nail changes such as clubbing, leukonychia (whitening), or onycholysis, affecting the nails of the hands and feet. [8] Onychomycosis (tinea) It is common in ballet dancers [9] Chemotherapy (cytotoxic agents like taxanes, vinca alkaloids and others) Chronic Renal ...
Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Mees' lines can look similar to injury to the nail, which should not be confused with true Mees' lines. [1]Mees' lines appear after an episode of poisoning with arsenic, [2] thallium or other heavy metals or selenium, [3] opioid MT-45, and can also appear if the subject is suffering from kidney failure. [4]
When the distal phalanges (bones nearest the fingertips) of corresponding fingers of opposite hands are directly opposed (place fingernails of same finger on opposite hands against each other, nail to nail), a small diamond-shaped "window" is normally apparent between the nailbeds. If this window is obliterated, the test is positive and ...
Onychorrhexis also known as brittle nails, is brittleness with breakage of fingernails or toenails. Paronychia is a bacterial or fungal infection where the nail and skin meet. Koilonychia is when the nail curves upwards (becomes spoon-shaped) due to an iron deficiency. The normal process of change is: brittle nails, straight nails, spoon-shaped ...
Carpal tunnel surgery is usually considered after other treatment options have failed, Melamed says. Other, less invasive treatments, like splinting and steroid injections, are typically tried first.
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...
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