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Salmeterol is a long-acting β 2 adrenergic receptor agonist (LABA) used in the treatment and prevention of asthma symptoms and control of chronic obstructive pulmonary disease (COPD) symptoms. [2] Symptoms of bronchospasm include shortness of breath, wheezing, coughing and chest tightness.
Indacaterol maleate—an ultra-long-acting beta-adrenoceptor agonist (ultra-LABA); [2] Glycopyrronium bromide (glycopyrrolate)—a muscarinic anticholinergic . Indacaterol maleate/glycopyrronium bromide is used as a maintenance bronchodilator treatment to relieve symptoms in adult patients with chronic obstructive pulmonary disease (COPD).
Aclidinium bromide/formoterol, sold under the brand names Duaklir and Brimica, is a fixed-dose combination medication for inhalation, used in the management of chronic obstructive pulmonary disease (COPD). [5] It consists of aclidinium bromide, a long-acting muscarinic antagonist, and formoterol, a long-acting β 2 agonist. [3] [4]
Formoterol is a long-acting beta-2 agonist. [3] [4] It attaches to receptors (targets) known as beta-2 receptors in the muscles of the airways. [3] [4] By attaching to these receptors, it causes the muscles to relax, which keeps the airways open and helps with the patient's breathing. [3] [4] Glycopyrronium bromide is a muscarinic receptor ...
Beta blockers vary in their lipophilicity (fat solubility) and in turn in their ability to cross the blood–brain barrier and exert effects in the central nervous system. [76] Beta blockers with greater blood–brain barrier permeability can have both neuropsychiatric therapeutic benefits and side effects, as well as adverse cognitive effects ...
The combination fluticasone furoate/umeclidinium bromide/vilanterol product is approved by the US Food and Drug Administration with an indication for the maintenance treatment of a chronic lung problem called chronic obstructive pulmonary disease (COPD) in adults who (1) have already tried fluticasone furoate/vilanterol (brand name Breo Ellipta) but are still experiencing symptoms of airway ...