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Gestational diabetes is a condition in which a woman without diabetes develops high blood sugar levels during pregnancy. [2] Gestational diabetes generally results in few symptoms; [2] however, obesity increases the rate of pre-eclampsia, cesarean sections, and embryo macrosomia, as well as gestational diabetes. [2]
Gestational diabetes is directly linked with obesity in offspring through adolescence. [87] Additionally, children whose mothers had diabetes are more likely to develop Type II diabetes. [88] Mothers who have gestational diabetes have a high chance of giving birth to very large infants (10 pounds (4.5 kg) or more). [71] This is a cause of ...
Pre-gestational diabetes can be classified as Type 1 or Type 2 depending on the physiological mechanism. Type 1 diabetes mellitus is an autoimmune disorder leading to destruction of insulin-producing cell in the pancreas; type 2 diabetes mellitus is associated with obesity and results from a combination of insulin resistance and insufficient insulin production.
The American Diabetes Association (ADA) is a United States-based nonprofit that seeks to educate the public about diabetes and to help those affected by it through funding research to manage, cure and prevent diabetes, including type 1 diabetes, type 2 diabetes, gestational diabetes, and pre-diabetes. It is a network of 565,000 volunteers which ...
IRS-1 protein is known to be involved in various types of cancer, including colorectal, [37] lung, [38] prostate and breast cancer. [39] IRS-1 integrates signalling from insulin receptor (InsR), insulin-like growth factor-1 receptor (IGF1R) and many other cytokine receptors and is elevated in β-catenin induced cells.
Nulliparity has been implicated in the development of various complications during pregnancy including preeclampsia, gestational diabetes and pre-term labor. [5] Long-term and permanent nulliparity (/ ˌ n ʌ l ɪ ˈ p ær ɪ t i /) are risk factors for breast cancer. For instance, a meta-analysis, published in 1990, of 8 population-based ...
Diabetes was the eighth leading cause of death in the United States in 2020. People with diabetes are twice as likely to develop heart disease or stroke as people without diabetes. There are three types of diabetes: Type 1, Type 2, and gestational (diabetes while pregnant). Type 2 diabetes accounts for 90%-95% of all cases. [1]
Neonatal diabetes is classified into three subtypes: permanent, transient, and syndromic; each with distinct genetic causes and symptoms. [5] Syndromic neonatal diabetes is the term for diabetes as just one component of any of several complex syndromes that affect neonates, including IPEX syndrome, Wolcott-Rallison syndrome, and Wolfram ...
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