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Nonsteroidal anti-inflammatory drug. Non-steroidal anti-inflammatory drugs[1][3] (NSAID) [1] are members of a therapeutic drug class which reduces pain, [4] decreases inflammation, decreases fever, [1] and prevents blood clots. Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of ...
NSAIDs caused no adverse effects on renal function in healthy dogs subjected to anesthesia. [11] [12] [13] Most healthy kidneys contain enough physiologic reserve to compensate for this NSAID-induced decrease in blood flow. However, those subjected to additional injury from phenacetin or paracetamol may progress to analgesic nephropathy.
Common side effects include heartburn, nausea, indigestion, and abdominal pain. [8] Compared to other NSAIDs, it may have other side effects such as gastrointestinal bleeding. [10] Long-term use has been associated with kidney failure, and rarely liver failure, and it can exacerbate the condition of patients with heart failure. [8]
Ketorolac, sold under the brand name Toradol among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain. [3][4] Specifically it is recommended for moderate to severe pain. [5] Recommended duration of treatment is less than six days, [4] and in Switzerland not more than seven days (parenterally two days). [6]
Nephrotoxicity. Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
Common side effects include dizziness, headache, bruising, allergic reactions, heartburn, and stomach pain. [8] Severe side effects include an increased risk of heart disease, stroke, gastrointestinal bleeding, and stomach ulcers. [8] The heart disease risk may be lower than with other NSAIDs. [8] It is not recommended in people with kidney ...