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With age inevitable biological changes occur that increase the risk of illness and disability. UNFPA states that: [122] "A life-cycle approach to health care – one that starts early, continues through the reproductive years and lasts into old age – is essential for the physical and emotional well-being of older persons, and, indeed, all people.
Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. The hallmarks of aging are the types of biochemical changes that occur in all organisms that experience biological aging and lead to a progressive loss of physiological integrity, impaired function and, eventually, death.
It is sometimes referred to as chronological ageing and is an inherent degenerative process due to declining physiologic functions and capacities. Such an ageing process may include qualitative and quantitative changes and includes diminished or defective synthesis of collagen and elastin in the dermis.
Stroke could occur at any age, including in childhood, the risk of stroke increases exponentially from 30 years of age, and the cause varies by age. [35] Advanced age is one of the most significant stroke risk factors. 95% of strokes occur in people age 45 and older, and two-thirds of strokes occur in those over the age of 65.
Senescence (/ s ɪ ˈ n ɛ s ə n s /) or biological aging is the gradual deterioration of functional characteristics in living organisms. Whole organism senescence involves an increase in death rates or a decrease in fecundity with increasing age, at least in the later part of an organism's life cycle.
As adult bodies undergo a variety of physical changes that cause health to decline, a higher risk of contracting a variety of illnesses, both physical and mental, is possible. [55] Cancer; Scientists have made a distinctive connection between aging and cancer. It has been shown that the majority of cancer cases occur in those over 50 years of ...
Intrinsic mortality is defined as mortality due to ageing, the physiological decline due to innate processes, whereas extrinsic mortality is the result of environmental factors such as for example predation, starvation, accidents and others. Flying animals such as bats, for example, have fewer predators, and therefore have a low extrinsic ...
Recent reports in model organisms suggest that as organisms age, there are distinct changes in the expression of genes at the single neuron level. [4] This page is an overview of the changes associated with human brain aging, including aging without concomitant diseases.