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In renal physiology, ultrafiltration occurs at the barrier between the blood and the filtrate in the glomerular capsule (Bowman's capsule) in the kidneys. As in nonbiological examples of ultrafiltration , pressure (in this case blood pressure ) and concentration gradients lead to a separation through a semipermeable membrane (provided by the ...
It contains the renal corpuscles and the renal tubules except for parts of the loop of Henle which descend into the renal medulla. It also contains blood vessels and cortical collecting ducts. The renal cortex is the part of the kidney where ultrafiltration occurs. [2] Erythropoietin is produced in the renal cortex. [3]
The kidney is responsible for about half of the total gluconeogenesis in fasting humans. The regulation of glucose production in the kidney is achieved by action of insulin, catecholamines and other hormones. [14] Renal gluconeogenesis takes place in the renal cortex.
Diagram showing Bowman's capsule as part of the renal corpuscle. The process of filtration of the blood in the Bowman's capsule is ultrafiltration, and the normal rate of filtration is 125 ml/min, equivalent to 80 times the daily blood volume. [citation needed] It is a major site for blood filtration (including glomerulus)
Tubular fluid is the fluid in the tubules of the kidney. It starts as a renal ultrafiltrate in the glomerulus , changes composition through the nephron , and ends up as urine leaving through the ureters .
The glomerular basement membrane of the kidney is the basal lamina layer of the glomerulus.The glomerular endothelial cells, the glomerular basement membrane, and the filtration slits between the podocytes perform the filtration function of the glomerulus, separating the blood in the capillaries from the filtrate that forms in Bowman's capsule. [1]
Its cell body has extending major or primary processes that form secondary processes as podocyte foot processes or pedicels. [6] The primary processes are held by microtubules and intermediate filaments. The foot processes have an actin-based cytoskeleton. [6] Podocytes are found lining the Bowman's capsules in the nephrons of the kidney.
The kidney has many functions, which a well-functioning kidney realizes by filtering blood in a process known as glomerular filtration. A major measure of kidney function is the glomerular filtration rate (GFR). The glomerular filtration rate is the flow rate of filtered fluid through the kidney.