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Holland Taylor as Evelyn Harper (seasons 1–9; recurring, seasons 10–12), Charlie and Alan's vain mother and the grandmother of Jake and Jenny. A high-powered Los Angeles broker/realtor, she is bisexual. Marin Hinkle as Judith Harper-Melnick (seasons 1–9; recurring, seasons 10–12), Alan's selfish, mean-spirited ex-wife and Jake and Milly ...