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Previous observations and the research of Gierman et al. proved that the activity of a domain has great impact on the expression of the genes located in it. And the genes within a RIDGE are co-expressed. However the constructs used by Gierman et al. were regulated by al full-time active promoter.
The apical ectodermal ridge (AER) is a structure that forms from the ectodermal cells at the distal end of each limb bud and acts as a major signaling center to ensure proper development of a limb. After the limb bud induces AER formation, the AER and limb mesenchyme —including the zone of polarizing activity (ZPA)—continue to communicate ...
The zone of polarizing activity (ZPA) is an area of mesenchyme that contains signals which instruct the developing limb bud to form along the anterior/posterior axis. Limb bud is undifferentiated mesenchyme enclosed by an ectoderm covering. Eventually, the limb bud develops into bones, tendons, muscles and joints.
A mammary ridge, or crest, usually stops growing at eight weeks and its length is regressed starting at the caudal end and extending cranially, [1] so that what remains is a round, ectodermic placode where the axilla develops. When shortening of the mammary crest is complete, the structure remains prominent in the areas where the mammary glands ...
Glacial activity may leave ridges in the form of moraines and eskers. An arête is a thin ridge of rock that is formed by glacial erosion. [2] Pressure ridge (ice) An ice pressure ridge is a ridge of deformed ice along the boundaries of individual ice floes when the ice floes on a lake or ocean collide and compress their edges.
Ridge (biology), a domain of the genome with a high gene expression Ridge (meteorology), an elongated region of relatively high atmospheric pressure Ridge detection, an image descriptor for capturing elongated objects that are brighter than their surrounding
In mice, the genital ridge houses the transcript for SRY, the Y-chromosomal gene responsible for sex determination in mammals. The urogenital ridge is made up of the gonadal anlage and the mesonephros. The mesonephros is involved in the development of the testis, but its role is in differentiation, and not determination. This is indicated by ...
The brow ridges are often not well expressed in human females, as pictured above in a female skull, and are most easily seen in profile. The brow ridge, or supraorbital ridge known as superciliary arch in medicine, is a bony ridge located above the eye sockets of all primates and some other animals.