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Prostate-specific antigen. Prostate-specific antigen (PSA) is secreted by the epithelial cells of the prostate gland and can be detected in a sample of blood. [14] PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. [15]
Created in 1992 by the American Urological Association, it originally lacked the eighth quality of life question, hence its original name: the American Urological Association symptom score (AUA-7). [1] World Health Organization International Consultation on BPH adopted the "eight question" index and labeled it the IPSS. [2]
Most medical guidelines recommend that men at high risk of prostate cancer (due to age, family history, ethnicity, or prior evidence of high blood PSA levels) be counseled on the risks and benefits of PSA testing, and be offered access to screening tests. [12] Medical guidelines generally recommend against screening for men over age 70, or with ...
The American Urological Association (AUA) is a professional association in the United States for urology professionals. [1] It has its headquarters at the William P. Didusch Center for Urologic History in Maryland. AUA works with many international organizations, representing urologists from across the world.
There are several reasons why PIN is the most likely prostate cancer precursor. [3] PIN is more common in men with prostate cancer. High grade PIN can be found in 85 to 100% of radical prostatectomy specimens, [4] nearby or even in connection with prostate cancer.
In men aged 55–69 who have been counseled on the known harms and potential benefits of prostate cancer screening, the U.S. Preventive Service Task Force May 2018 statement states, "The use of digital rectal examination as a screening modality is not recommended because there is a lack of evidence on the benefits."
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