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An atheroma, or atheromatous plaque, is an abnormal accumulation of material in the inner layer of an arterial wall. [1] [2]The material consists of mostly macrophage cells, [3] [4] or debris, containing lipids, calcium and a variable amount of fibrous connective tissue.
The brain is supplied with blood by the internal carotid arteries and also by the posterior cerebral arteries; the posterior communicating arteries connects the two systems. This provides redundancies or collaterals in the cerebral circulation so that, if one system is blocked or narrowed, the other can take over.
Foam cells form the fatty streaks of the plaques of atheroma in the tunica intima of arteries. Foam cells are not dangerous as such, but can become a problem when they accumulate at particular foci thus creating a necrotic centre of atherosclerosis .
Cerebral atherosclerosis is a type of atherosclerosis where build-up of plaque in the blood vessels of the brain occurs. Some of the main components of the plaques are connective tissue, extracellular matrix, including collagen, proteoglycans, fibronectin, and elastic fibers; crystalline cholesterol, cholesteryl esters, and phospholipids; cells such as monocyte derived macrophages, T ...
In brain tissue, a biochemical cascade known as the ischemic cascade is triggered when the tissue becomes ischemic, potentially resulting in damage to and the death of brain cells. Medical professionals must take steps to maintain proper CBF in patients who have conditions like shock , stroke , cerebral edema , and traumatic brain injury .
In 1858 doctor Thomas Inman described four of thirty discovered cases with cerebral softening. Each case was similar to the previous article. There was some atheroma in the internal brain arteries that led to the cerebral softening of the left side of the brain around the left lateral ventricle, thalamus and corpus striatum. There were similar ...
"Anatomy diagram: 13048.000-1". Roche Lexicon - illustrated navigator. Elsevier. Archived from the original on 2014-01-01. The arteries of the base of the brain. Posterior inferior cerebellar artery labeled at bottom. The temporal pole of the cerebrum and a portion of the cerebellar hemisphere have been removed on the right side. Inferior ...
This artery may form an anastomosis with the posterior cerebral artery. Callosal marginal artery : A commonly present terminal branch of the ACA, which bifurcates from the pericallosal artery . This artery in turn branches into the medial frontal arteries (anterior, intermediate, posterior), and the paracentral artery , with the cingulate ...