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The trial investigates new approaches for men with metastatic and locally advanced prostate cancer. [1] 117 hospitals in the UK and Switzerland are involved with over 10,000 men are expected to take part in the trial. [2] The men are randomly assigned to one of a number of "arms". The primary outcome by which the arms were judged is overall ...
Trial 1 included two groups of participants, some with recently diagnosed prostate cancer and others with suspicious findings on standard tests. [7] Trial 2 included participants who were treated for prostate cancer before, but there was suspicion that the cancer was spreading because of rising prostate-specific antigen. [ 7 ]
The trial will study 550 men. ... which will study talazoparib and enzalutamide in patients suffering from metastatic castration-sensitive prostate cancer (mCSPC). The trial will evaluate the ...
In a large-scale clinical trial that compared 750 mg/day flutamide and 250 mg/day CPA monotherapies in the treatment of men with prostate cancer, the two drugs were found to have equivalent effectiveness on all endpoints. [82]
The candidate, JANX007, reduced prostate-specific (PSA) antigen levels in a majority of the 23 patients who received the drug, the company said late on Monday, adding that deeper reductions were ...
Efficacy was evaluated in VISION, [21] a randomized (2:1), multicenter, open-label trial that evaluated lutetium (177 Lu) vipivotide tetraxetan plus best standard of care (BSoC) (n=551) or BSoC alone (n=280) in men with progressive, prostate-specific membrane antigen (PSMA)-positive metastatic castration-resistant prostate cancer (mCRPC). [6]
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