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Simvastatin also reduced the numbers of other events like heart attacks, strokes, and revascularizations and MI significantly. [11] The Heart Protection Study evaluated the effects of simvastatin in people with risk factors including existing cardiovascular disease, diabetes, or stroke, but having relatively low LDL cholesterol. In this trial ...
Ezetimibe/simvastatin is a drug combination used for the treatment of dyslipidemia. ... Pregnancy and breast feeding; Side effects
[17] [18] The medication appears to work equally well regardless of sex, [19] although some sex-related differences in treatment response were described. [20] If there is an underlying history of cardiovascular disease, it has a significant impact on the effects of statin.
Possibly taking certain medications during pregnancy, such as statins. Possibly smoking or drinking during pregnancy. Poorly controlled diabetes during pregnancy. ... Cardiovascular Disease Treatment.
Smoking during pregnancy is dangerous to the unborn baby and may cause pre-term birth, birth defects such as cleft lip or cleft palate, or miscarriage. [93] [80] Tobacco is the most commonly used substance among pregnant women, at 25%. [87] [94] Nicotine crosses the placenta and accumulates within fetal tissues.
The effects of not getting enough sleep can bleed into your daily life. ... Pregnancy or having a new baby. ... Getting treatment for existing medical or mental health conditions.
Among atypical adverse effects, myositis can occur in patients under gemfibrozil therapy, especially in those with renal insufficiency or under co-treatment with statins. In contrast, the risk of myopathy is much lower if fenofibrate is used in replacement of gemfibrozil owing to its different pharmacokinetic pathway.
While there have been concerns about side-effects associated with statins (myopathy and rhabdomyolysis), these were rare in this study. [citation needed] The number needed to treat in the study was 57 to postpone one death and 19 to prevent one cardiovascular "event" (in those taking the drug simvastatin for 5 years). There was no mortality ...