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NeilMed Pharmaceuticals was founded by Ketan C. Mehta, [6] [7] a pulmonary and critical-care physician, and Nina Mehta in the year 2000. [8] [9] [10] It started as a side project in 1999 to build a device that could be used to effectively and naturally rinse the sinuses for sinusitis sufferers known as NeilMed Sinus Rinse.
Midodrine is a prodrug which forms the active metabolite, desglymidodrine, which is an α 1-adrenergic receptor agonist and exerts its actions via activation of α 1-adrenergic receptors of the arteriolar and venous vasculature, producing an increase in vascular tone and elevation of blood pressure.
Adverse effects include nasal irritation, nosebleeds, headache, and drainage after the irrigation is done. It is generally well tolerated. [2] There is a risk of infection if the water is not sterile or the device is not cleaned after use. If the device is used improperly this can be harmful. [4]
Corticosteroid nasal sprays can be used to relieve the symptoms of sinusitis, hay fever, allergic rhinitis and non-allergic (perennial) rhinitis.They can reduce inflammation and histamine production in the nasal passages, and have been shown to relieve nasal congestion, runny nose, itchy nose and sneezing. [2]
New RSV vaccines are now available to help prevent serious infection in people over 60. Doctors explain the RSV vaccine and its side effects in older adults.
Berotralstat, sold under the brand name Orladeyo, is a medication used to prevent attacks of hereditary angioedema (HAE) in people aged twelve years and older. [3] [5] [7] [8] [4]