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Clindamycin was first made in 1966 from lincomycin. [11] [12] It is on the World Health Organization's List of Essential Medicines. [13] It is available as a generic medication. [14] [15] In 2022, it was the 147th most commonly prescribed medication in the United States, with more than 3 million prescriptions. [16] [17]
Specialty-specific studies have also been carried out, especially in high-risk surgery of the spine. One large Canadian study found that the spine-surgery SSI rate decreased 5.6% (from 7.2% to 1.6%) because of nasal aPDT combined with chlorhexidine bathing, saving on average $45–55 CAD per treated patient ($4.24 million CAD annually).
It contains clindamycin, as the phosphate, a lincosamide antibacterial; adapalene, a synthetic retinoid; and benzoyl peroxide, an oxidizing agent. [2] It is applied to the skin . [ 2 ]
Clindamycin/benzoyl peroxide, sold under the brand name Benzaclin among others, is a topical gel used for the treatment of acne. [7] It is a fixed-dose combination of clindamycin , as the phosphate, an antibiotic ; and benzoyl peroxide , an antiseptic .
Chances are, you adhered to many of these falsehoods without realizing the damage they may have caused. Fortunately, sites like Reddit provide medical professionals with a platform to debunk some ...
Out of the many families of multidrug resistance pumps, lincosamides are most commonly shunted through pumps belonging to the resistance-nodulation-cell division superfamily. [17] Staphylococci express efflux pumps with specificity for 14 and 15 member ring macrolides and streptogramin B, but not lincosamide molecules.
Ukraine is far from the only country affected by this issue: around 1.4 million people globally died of a AMR infection in 2021, and in the UK there were 66,730 serious antibiotic-resistant ...
Penicillin G, 5 million units IV initial dose, then 3 million units every 4 hours until delivery or ampicillin, 2 g IV initial dose, then 1 g IV every 4 hours until delivery. [ 4 ] [ 12 ] [ 14 ] Appropriate IAP in GBS colonized women should start as soon as possible once labour starts or the waters have broken.