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Treponema pallidum pallidum is a motile spirochete that is generally acquired by close sexual contact, entering the host via breaches in squamous or columnar epithelium. The organism can also be transmitted to a fetus by transplacental passage during the later stages of pregnancy, giving rise to congenital syphilis. [ 54 ]
Treponema is a genus of spiral-shaped bacteria. The major treponeme species of human pathogens is Treponema pallidum, whose subspecies are responsible for diseases such as syphilis, bejel, and yaws. Treponema carateum is the cause of pinta. [2] Treponema paraluiscuniculi is associated with syphilis in rabbits. [3]
Treponema pallidum subspecies which cause treponematoses such as syphilis and yaws. Brachyspira pilosicoli and Brachyspira aalborgi, which cause intestinal spirochaetosis [16] Salvarsan, the first partially organic synthetic antimicrobial drug in medical history, was effective against spirochaetes and primarily used to cure syphilis.
Treponema pallidum subspecies pallidum is a spiral-shaped, Gram-negative, highly mobile bacterium. [ 11 ] [ 22 ] Two other human diseases are caused by related Treponema pallidum subspecies, yaws (subspecies pertenue ) and bejel (subspecies endemicum ), and one further caused by the very closely related Treponema carateum , pinta .
Histopathology of Treponema pallidum spirochetes using a modified Steiner silver stain Scientific classification; Domain: Bacteria: Phylum: Spirochaetota: Class: Spirochaetia: Order: Spirochaetales: Family: Treponemataceae Robinson 1948 [1] (Approved Lists 1980) [2] Genera "Ca. Avitreponema" Brucepastera "Ca. Gallitreponema" Teretinema ...
The Spirochaetales are an order of spirochete bacteria. Some species within this order are known to causes syphilis , Lyme disease , relapsing fever , and other illnesses. [ 3 ]
Bejel, or endemic syphilis, is a chronic skin and tissue disease caused by infection by the endemicum subspecies of the spirochete Treponema pallidum.Bejel is one of the "endemic treponematoses" (endemic infections caused by spiral-shaped bacteria called treponemes), a group that also includes yaws and pinta.
The genus is named after French biologist Amédée Borrel (1867–1936), who first documented the distinction between a species of Borrelia, B. anserina, and the other known type of spirochete at the time, Treponema pallidum. [4] This bacterium must be viewed using dark-field microscopy, [5] which make the cells appear white against a dark ...