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If you take Qsymia, the starting dose is 3.75mg of phentermine and 23mg of topiramate daily for 14 days. The dose then increases to 7.5mg of phentermine and 46mg of topiramate daily for 90 days.
Phentermine and topiramate was developed by Vivus, a California pharmaceutical company. In December 2009, Vivus, Inc. submitted a new drug application (NDA) to the FDA and on 1 March 2010, Vivus, Inc. announced that the FDA accepted the NDA for review.
Qsymia. Qsymia is a combo of topiramate and phentermine, which is an appetite suppressant. You take one tablet each morning. ... Your dose might start at 3.75mg of phentermine and 23mg of ...
In 2022, it was the 149th most commonly prescribed medication in the United States, with more than 3 million prescriptions. [12] [13] Phentermine was withdrawn from the market in the United Kingdom in 2000, while the combination medication fen-phen, of which it was a part, was withdrawn from the market in 1997 due to side effects of ...
A 2010 phase 2 trial found cetilistat significantly reduced weight and was better tolerated than orlistat. [34] SGLT2 inhibitors cause the loss of 60–100 grams (2.1–3.5 oz) glucose in the urine each day and are associated with a modest, sustained weight loss of 1.5–2 kilograms (3.3–4.4 lb) in people with type 2 diabetes.
Vivus also developed an obesity drug, Qnexa (now called Qsymia), a combination of phentermine and topiramate, two existing weight-loss drugs. [4] On July 17, 2012, The U.S. Food and Drug Administration approved Qsymia ( phentermine and topiramate extended-release ), made by Vivus, as an addition to a reduced-calorie diet and exercise for ...