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Bladder cancer is much more common in men than women; around 1.1% of men and 0.27% of women develop bladder cancer. [2] This makes bladder cancer the sixth most common cancer in men, and the seventeenth in women. [69] When women are diagnosed with bladder cancer, they tend to have more advanced disease and consequently a poorer prognosis. [69]
Transitional cell carcinoma is the leading type of bladder cancer, occurring in 9 out of 10 cases. [11] It is also the leading cause of cancer of the ureter, urethra, and urachus, and the second leading cause of cancer of the kidney. Transitional cell carcinoma can develop in two different ways.
It accounts for 95% of bladder cancer cases and bladder cancer is in the top 10 most common malignancy disease in the world and is associated with approximately 200,000 deaths per year in the US. [2] [3] It is the second most common type of kidney cancer, but accounts for only five to 10 percent of all primary renal malignant tumors. [4]
Transitional cell carcinoma is the most common type of bladder cancer and cancer of the ureter, urethra, renal pelvis, the ureters, the bladder, and parts of the urethra and urachus. [ 1 ] [ 2 ] It originates from tissue lining the inner surface of these hollow organs - transitional epithelium .
Cancer is a group of diseases that involve abnormal increases in the number of cells, with the potential to invade or spread to other parts of the body. [1] Not all tumors or lumps are cancerous; benign tumors are not classified as being cancer because they do not spread to other parts of the body. [ 1 ]
A papillary tumor is a tumor shaped like a small mushroom, with its stem attached to the epithelial layer (inner lining) of an organ. [ 1 ] [ 2 ] It consists of papillae , which are outgrowths that consist of stroma with at least one central blood vessel, surrounded by epithelium.
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