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Limbic encephalitis refers to inflammatory disease confined to the limbic system of the brain. The clinical presentation often includes disorientation, disinhibition, memory loss, seizures, and behavioral anomalies. MRI imaging reveals T2 hyperintensity in the structures of the medial temporal lobes, and in some cases, other limbic structures ...
Limbic encephalitis is a form of encephalitis, a disease characterized by inflammation of the brain. [1] Limbic encephalitis is caused by autoimmunity : an abnormal state where the body produces antibodies against itself.
Superior limbic keratoconjunctivitis (SLK, Théodore's syndrome [1]) is a disease of the eye [2] characterized by episodes of recurrent inflammation of the superior cornea and limbus, as well as of the superior tarsal and bulbar conjunctiva. [3] It was first described by F. H. Théodore in 1963. [4]
“Limbic” is related to the brain areas first involved, “age-related” and the name “LATE” itself refer to the onset of disease usually in persons aged 80 or older. “ TDP-43 ” indicates the aberrant mis-folded protein (or proteinopathy ) deposits in the brain that characterize LATE, and “ encephalopathy ” means illness of brain.
ICD-10 is the 10th revision of the International Classification of Diseases (ICD), a medical classification list by the World Health Organization (WHO). It contains codes for diseases, signs and symptoms, abnormal findings, complaints, social circumstances, and external causes of injury or diseases. [1]
The term limbic system was introduced in 1952 by Paul MacLean to describe the set of structures that line the deep edge of the cortex (Latin limbus meaning border): [18] These include the hippocampus, cingulate cortex, olfactory cortex, and amygdala. Paul MacLean later suggested that the limbic structures comprise the neural basis of emotion.
The ICD-11 includes bodily distress disorder, which bears similarities to somatic symptom disorder. While both conditions involve somatic symptoms, bodily distress disorder appears to be more strongly associated with the experience of physical symptoms, whereas somatic symptom disorder is more closely linked to psychological distress. [ 37 ]
[10] [2] The common mesial temporal lobe seizure auras include a rising epigastric feeling, abdominal discomfort, taste (gustatory), smell (olfactory), tingling (somatosensory), fear, déjà vu, jamais vu, flushing, or rapid heart rate (tachycardia). [2] A person may then stare blankly, appear motionless (behavioral arrest) and lose awareness. [2]