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Cardiomyopathies are either confined to the heart or are part of a generalized systemic disorder, both often leading to cardiovascular death or progressive heart failure-related disability. Other diseases that cause heart muscle dysfunction are excluded, such as coronary artery disease, hypertension, or abnormalities of the heart valves. [17]
Additionally, the weakened heart muscle may not be able to effectively pump blood to the lungs, leading to the accumulation of fluid in the lungs, a condition known as pulmonary edema. [ 7 ] Another potential complication of alcoholic cardiomyopathy is the development of arrhythmias, or abnormal heart rhythms. [ 7 ]
Model of a normal heart (left); and a weakened heart, with over-stretched muscle and dilation of left ventricle (right); both during diastole. Heart failure is caused by any condition that reduces the efficiency of the heart muscle, through damage or overloading.
The main pathophysiology of heart failure is a reduction in the efficiency of the heart muscle, through damage or overloading. As such, it can be caused by a wide number of conditions, including myocardial infarction (in which the heart muscle is starved of oxygen and dies), hypertension (which increases the force of contraction needed to pump blood) and cardiac amyloidosis (in which misfolded ...
heart failure — reduced cardiac efficiency due to a weakened heart muscle may ... progression of atherosclerosis and reduced risk of death from heart disease (and reduced all-cause mortality). ...
Angina, also known as angina pectoris, is chest pain or pressure, usually caused by insufficient blood flow to the heart muscle (myocardium). [2] It is most commonly a symptom of coronary artery disease. [2] Angina is typically the result of partial obstruction or spasm of the arteries that supply blood to the heart muscle. [3]
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