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The T helper cells (T h cells), also known as CD4 + cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune system. They aid the activity of other immune cells by releasing cytokines .
CD4+ T helper cells are white blood cells that are an essential part of the human immune system. They are often referred to as CD4 cells, T helper cells or T4 cells. They are called helper cells because one of their main roles is to send signals to other types of immune cells, including CD8 killer cells, which then destroy the infectious ...
T helper cells (T H cells) assist other lymphocytes, including the maturation of B cells into plasma cells and memory B cells, and activation of cytotoxic T cells and macrophages. These cells are also known as CD4 + T cells as they express the CD4 glycoprotein on their surfaces.
Follicular helper T cells (also known as T follicular helper cells and abbreviated as T FH), are antigen-experienced CD4 + T cells found in the periphery within B cell follicles of secondary lymphoid organs such as lymph nodes, spleen and Peyer's patches, and are identified by their constitutive expression of the B cell follicle homing receptor CXCR5. [1]
The activation of a naive helper T-cell causes it to release cytokines, which influences the activity of many cell types, including the APC (Antigen-Presenting Cell) that activated it. Helper T-cells require a much milder activation stimulus than cytotoxic T cells. Helper T cells can provide extra signals that "help" activate cytotoxic cells. [6]
A third category called T helper 17 cells (T H 17) were also discovered which are named after their secretion of Interleukin 17. CD8 + cytotoxic T-cells may also be categorized as: [5] T c 1 cells, T c 2 cells. Similarly to CD4 + T H cells, a third category called T C 17 were discovered that also secrete IL-17.
Antigen presentation stimulates T cells to become either "cytotoxic" CD8+ cells or "helper" CD4+ cells.. Antigen presentation is a vital immune process that is essential for T cell immune response triggering.
T helper 3 cells (T h 3) are a subset of T lymphocytes with immunoregulary and immunosuppressive functions, that can be induced by administration of foreign oral antigen. [1] T h 3 cells act mainly through the secretion of anti-inflammatory cytokine transforming growth factor beta ().