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  2. mRNA vaccine - Wikipedia

    en.wikipedia.org/wiki/MRNA_vaccine

    Self-amplifying mRNA (saRNA) vaccines replicate their mRNA after transfection. [100] Self-amplifying mRNA has two open reading frames. The first frame, like conventional mRNA, codes for the antigen of interest. The second frame codes for an RNA-dependent RNA polymerase (and its helper proteins) which replicates the mRNA construct in the cell.

  3. New COVID vaccines are here. What to know about latest ... - AOL

    www.aol.com/finance/covid-vaccines-know-latest...

    Single pediatric doses for children 5 to 11 contain 10 μg of mRNA, while doses given in a series for children 6 months to 4 years contain 3 μg of mRNA. Spikevax is the brand name of Moderna’s ...

  4. Vaccine efficacy - Wikipedia

    en.wikipedia.org/wiki/Vaccine_efficacy

    Vaccine efficacy differs from vaccine effectiveness in the same way that an explanatory clinical trial differs from an intention-to-treat trial [clarification needed]: vaccine efficacy shows how effective a vaccine could be given ideal circumstances and 100% vaccine uptake (such as the conditions within a controlled clinical trial); vaccine effectiveness measures how well a vaccine performs ...

  5. Katalin Karikó - Wikipedia

    en.wikipedia.org/wiki/Katalin_Karikó

    The mRNA vaccines were developed and approved for use at unprecedented speed, and demonstrated over 90% efficacy. In addition to vaccines for infectious diseases, mRNA has potential applications in treatment of cancer, cardiovascular and metabolic diseases [59] [60] [61] including ischemia. [62]

  6. Moderna COVID-19 vaccine - Wikipedia

    en.wikipedia.org/wiki/Moderna_COVID-19_vaccine

    In 2020, Moderna obtained purchase agreements for mRNA-1273 with the European Union for 160 million doses and with Canada for up to 56 million doses. [ 232 ] [ 233 ] In December 2020, a tweet by the Belgium Budget State Secretary revealed the E.U. would pay US$18 per dose, while The New York Times reported that the US would pay US$15 per dose.

  7. COVID-19 vaccine - Wikipedia

    en.wikipedia.org/wiki/COVID-19_vaccine

    How COVID‑19 vaccines work. The video shows the process of vaccination, from injection with RNA or viral vector vaccines, to uptake and translation, and on to immune system stimulation and effect. Part of a series on the COVID-19 pandemic Scientifically accurate atomic model of the external structure of SARS-CoV-2. Each "ball" is an atom. COVID-19 (disease) SARS-CoV-2 (virus) Cases Deaths ...